Ruth Brown

Genetics Scientist

Ruth Brown is a Genetics Scientist in the mitochondrial genetics team within the Oxford Medical Genetics Laboratories. She obtained a MSc in Biochemistry and also a BA from the University of Sydney.  Ruth has a long term interest in human genetics which began in the Genetics Laboratory, University of Oxford where she developed skills in early gene mapping techniques, including somatic cell hybrid studies and in situ hybridisation. Using these techniques she was involved in mapping the PDHA1 gene to the X chromosome and also in the identification of a large complementation group among cytochrome oxidase deficient patients, who were subsequently shown to have mutations in the SURF1 gene. She has a particular interest in the genetics of metabolic disorders and for the past several years her main area of work has been in the field of Mitochondrial Disease.