Mitochondrial diseases are an important group of inherited disorders that result in a defective mitochondrial respiratory chain.

Together they form an important group of inherited disorders, yet management of these conditions remains a poorly researched area and there is little expert advice available for the treatment of specific aspects of mitochondrial disease. Multi system involvement is also common and this can pose additional management dilemmas for doctors.

The Newcastle Mitochondrial Disease Guidelines aim to provide expert guidance to health professionals on the management of specific aspects of Mitochondrial Disease.

These guidelines have been developed using consensus expert opinion sourced from the NHS Rare Mitochondrial Disorders Service in Newcastle with associated experts from other hospitals.

Anaesthesia & Peri-Operative Guidelines

Cardiology Guidelines

Diabetes Guidelines

Epilepsy Guidelines

Gastrointestinal Guidelines

Neuropathy Guidelines

Ophthalmology Guidelines

Pregnancy Guidelines

Respiratory Guidelines

Stroke Like Episode Guidelines

Physiotherapy Guidelines

Safety of Drug Use Consensus Guidelines

Genetic Testing for Mitochondrial Disorders; The United Kingdom Best Practice Guidelines